the effect of exercise therapy on cognitive functions in multiple sclerosis patients: a pilot study

Authors

bahram sangelaji school of physiotherapy, otago university, new zealand and iranian multiple sclerosis society rehabilitation centre, tehran, iran.

fatemeh estebsari department of community health nursing, school of nursing and midwifery, shahidbeheshti university of medical sciences, tehran, iran.

seyed massood nabavi neurology department of mostafa hospital, shahed university, tehran, iran.سازمان اصلی تایید شده: دانشگاه شاهد (shahed university)

ensiyeh jamshidi community based participatory research center, iranian institute for reduction of high-risk behaviors, department of health education and promotion, school of public health, tehran university of medical sciences, tehran, iranسازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (tehran university of medical sciences)

abstract

background: the positive impacts of exercise therapy on patients’ cognitive problems still remain unknown. this study was a pilot intervention to examine the effects of combined exercise on the cognitive problems of patients with multiple sclerosis (ms) in iranian ms society over 2012 to 2013.   methods : this quasi-experimental research was carried out in the form of a pretest/posttest study. forty two patients with ms were selected from those visiting the rehabilitation center of iranian ms society, using non-probability convenience sampling. the expanded disability status scale (edss) of each patient was recorded before the intervention and brief repeatable battery of neuropsychological (brb-n) test was administered before and after the intervention. the data were analyzed using the analytical tests such as wilcoxon test.   results : of 21 participants, 17 subjects (82%, n=14) female with mean (±sd) age of 37 (±9.98) years and mean (±sd) edss of 2.35 (±0.90) completed all stages of the study. changes in long-term storage and permanent long-term retrieval of information after the intervention were statistically significant (p< 0.001). in addition, the change in the average of total delay after the intervention was also significant by 1.11 (p< 0.001).   conclusion : our study confirmed the possibility of change in the cognitive abilities of ms patients through physical interventions. this finding emphasizes the necessity of more clinical examinations and increases the hopes for new rehabilitation methods for the disorder.

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Journal title:
medical journal of islamic republic of iran

جلد ۲۹، شماره ۱، صفحات ۳۶۶-۳۷۴

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